Synthesis of. alpha.-methylene. beta.-lactones, novel heterocycles

…, N Dachs Grau, L Hasemann, B Nestler…

Index: Adam, Waldemar; Albert, Rainer; Grau, Nuria Dachs; Hasemann, Ludwig; Nestler, Bernd; et al. Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5778 - 5781

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Citation Number: 28

Abstract

Triphenylphosphine deoxygenation of &alkyl, B, B-dialkyl-, and@,@-spirocycloalkyl- substituted a-methylene-@-peroxy lactones 3a-k, which are readily available by photooxygenation of the corresponding a,@-unsaturated carboxylic acids 1, and cyclization of the resulting a-methylene-b-hydroperoxy acids 2 constitute a convenient method for the preparation of a variety of a-methylene &lactones 5. Alternatively, the a-methylene-8- ...