Au-Catalyzed Formation of Functionalized Quinolines from 2-Alkynyl Arylazide Derivatives

C Gronnier, G Boissonnat, F Gagosz

Index: Gronnier, Colombe; Boissonnat, Guillaume; Gagosz, Fabien Organic Letters, 2013 , vol. 15, # 16 p. 4234 - 4237

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Citation Number: 39

Abstract

A new method for converting 2-alkynyl arylazide derivatives into functionalized polysubstituted quinolines following a gold-catalyzed 1, 3-acetoxy shift/cyclization/1, 2-group shift sequence has been developed. This transformation proceeds under mild reaction conditions, is efficient, and tolerates a large variety of functional groups.