Steroids

Preparation of 16-formylestradiol and the 16-(α-methylenebutanolide) derivative

OA Akanni, BA Marple

Index: Akanni, Olufemi A.; Marple, Brian A. Steroids, 1993 , vol. 58, # 5 p. 234 - 238

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Citation Number: 3

Abstract

Abstract Route tot he preparation of 16-formylestradiol are described. Estronen was converted to (E)-16-methoxy-methylene estrone via the 16-hydroxymethylene estrone. Reduction of themethoxymethylene estrone with NaBH 4 in the presence of CeCl 3 gave ...