Palladium-catalyzed stereocontrolled vinylation of azoles and phenothiazine

…, DN Kazyul'kin, IP Beletskaya, AZ Voskoboynikov

Index: Lebedev, Artyom Y.; Izmer, Vyatcheslav V.; Kazyul'kin, Denis N.; Beletskaya, Irina P.; Voskoboynikov, Alexander Z. Organic Letters, 2002 , vol. 4, # 4 p. 623 - 626

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Citation Number: 94

Abstract

Vinylation of various azoles (pyrrole, indole, carbazole, and their derivatives) and phenothiazine with vinyl bromides catalyzed by palladium-phosphine complexes results in the respective N-vinylazoles in 30-99% yields. This reaction with cis-and trans-β- bromostyrenes is stereospecific giving the respective products with full retention of configuration.

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