New synthesis of sulphonylureas

R Tull, RC O'Neill, EP McCarthy, JJ Pappas…

Index: Tull,R. et al. Journal of the Chemical Society [Section] C: Organic, 1967 , p. 701 - 702

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Citation Number: 4

Abstract

1 -Alkyl-3-arylsulphonylureas have been synthesised by the reaction of sym-l,3-dialkylureas with aryl sulphon- amides. The mixed sulphonylureas are formed in good yield by virtue of the symmetry possessed by the dialkylurea component. ... Merck Sharp 8 Dohme Research Laboratories, Merck & Co., Inc., Rahway, New Jersey, USA ... THE sulphonylureas are an important class of com- pounds owing to their efficacy as oral hypoglycEmic agents, and their ...