Synthesis of γ-nitro aliphatic methyl esters via Michael additions promoted by microwave irradiation

J Escalante, FD Díaz-Coutiño

Index: Escalante, Jaime; Francisco, D. Diaz-Coutino Molecules, 2009 , vol. 14, # 4 p. 1595 - 1604

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Citation Number: 12

Abstract

Abstract: A simple and efficient protocol has been developed for the direct synthesis of γ- nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provided cleaner reactions.