Medicinal Chemistry Research

Synthesis of novel porphyrin-based lipids and their antibacterial activity

A Velidandi, KK Gadidasu, VS Patri

Index: Velidandi, Amarnath; Gadidasu, Kranthi Kumar; Patri, V.Srilakshmi Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 1068 - 1073

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Citation Number: 2

Abstract

Abstract The purpose of this study was to investigate the antibacterial activity of newly developed cationic amphiphilic lipids having porphyrin as head group against two types of gram-positive bacteria and three types of gram-negative bacteria. The antibacterial activity of quantitatively prepared porphyrin-based amphiphilic lipids is evaluated by the disc-diffusion method against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Klebsiella ...

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