Organic Letters

One-Pot Reactions for Modular Synthesis of Polysubstituted and Fused Pyridines

Z Song, X Huang, W Yi, W Zhang

Index: Li, Da-Peng; Zhang, Guang-Liang; An, Li-Tao; Zou, Jian-Ping; Zhang, Wei Green Chemistry, 2011 , vol. 13, # 3 p. 594 - 597

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Abstract

A 2-fluoro-1, 3-dicarbonyl-initiated one-pot Michael addition/[5+ 1] annulation/ dehydrofluorinative aromatization reaction sequence is introduced for regioselective synthesis of di-, tri-, tetra-, and pentasubstituted pyridines as well as fused pyridines. This