Efficient synthesis of unsymmetrical disulfides through sulfenic acids

…, A Barattucci, P Bonaccorsi

Index: Aversa, Maria Chiara; Barattucci, Anna; Bonaccorsi, Paola European Journal of Organic Chemistry, 2009 , # 36 p. 6355 - 6359

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Citation Number: 3

Abstract

Abstract Unsymmetrical disulfides, some of which are biologically interesting, were prepared by the in situ generation of sulfenic acids from suitable sulfinyl precursors and their coupling with various thiols. This methodology represents an efficient and mild procedure to obtain disulfides in excellent yields. It allows the presence of base/acid and/or thermolabile functional groups in both the sulfenic acid and the thiol on the basis of the choice of ...