Copper (II) Bromide/Boron Trifluoride Etherate??Cocatalyzed Cyclization of Ketene Dithioacetals and p??Quinones: a Mild and General Approach to Polyfunctionalized …

Y Liu, M Wang, H Yuan, Q Liu

Index: Liu, Yingjie; Wang, Mang; Yuan, Hongjuan; Liu, Qun Advanced Synthesis and Catalysis, 2010 , vol. 352, # 5 p. 884 - 892

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Citation Number: 32

Abstract

Abstract A new application of copper (II) bromide-activated ketene dithioacetals as nucleophiles in organic chemistry has been developed. Under the cocatalysis of copper (II) bromide (2.0 mol%) and boron trifluoride etherate (10 mol%), the conjugate addition and sequential cyclization of α-electron-withdrawing group-substituted ketene dithioacetals with p-quinones in acetonitrile at room temperature gave a variety of benzofurans. This formal [ ...