Highly Chemo??, Regio??, and Enantioselective Rhodium??Catalyzed Cross??Cyclotrimerization of Two Different Alkynes with Alkenes

…, M Kobayashi, K Noguchi, K Tanaka

Index: Hara, Jun; Ishida, Mana; Kobayashi, Masayuki; Noguchi, Keiichi; Tanaka, Ken Angewandte Chemie - International Edition, 2014 , vol. 53, # 11 p. 2956 - 2959 Angew. Chem., 2014 , vol. 53, # 11 p. 4

Full Text: HTML

Citation Number: 20

Abstract

Abstract It has been established that a cationic rhodium (I)/(R)-tol-binap complex catalyzes the cross-cyclotrimerization of silylacetylenes, di-tert-butyl acetylenedicarboxylates, and acrylamides with excellent chemo-, regio-, and enantioselectivities. Unsymmetrical alkynoates can also be employed in place of di-tert-butyl acetylenedicarboxylate for this process, but with reduced chemoselectivity.