Enantioselective synthesis of (+)-α-vetivone through the Michael reaction of chiral imines

G Revial, I Jabin, M Pfau

Index: Revial, Gilbert; Jabin, Ivan; Pfau, Michel Tetrahedron Asymmetry, 2000 , vol. 11, # 24 p. 4975 - 4983

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Citation Number: 24

Abstract

More than 60 years ago, Pfau and Plattner isolated from vetiver oil (Vetiveria zizanioides Stapf) its most important odoriferous constituent which they named α-vetivone. 4 The structure of the compound, belonging to the eremophilane group of sesquiterpenoids, was established about 30 years later independently by de Mayo 5., and and Marshall. 6 Syntheses of racemic α-vetivone 7., 8. and 9. as well as a hemi-synthesis of (+)-α-vetivone from (−)-β-pinene 10 ...