New NO??Donors with Antithrombotic and Vasodilating Activities, Part 16 3??Amino??1, 2, 4??oxadiazol??5??ones as Prodrugs for Hydroxyguanidines

K Rehse, S Bade

Index: Kaiser; Thurston Journal of Organic Chemistry, 1952 , vol. 17, p. 185,188

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Citation Number: 5

Abstract

... The addition of hydroxylamine to the hydroxyguanidine 5 and its cyclization to the oxadiaz- olone 6 occur in polar organic solvents like DMSO or DMFA at room ... Chemistry" ... C=O).- 'H-NMR ([D]6DMSO): 6 = 1.25 (t, J = 7 Hz, 3 H, CHZ-CH~), 3.15 (s, 3H, N-CH3), 4.26 (q, J = 7 Hz ...