New and efficient synthesis of 6, 11-dihydro-11-ethyl-5H-dibenz [b, e] azepine derivatives starting from N-benzylanilines via amino-Claisen and Friedel-Crafts …
…, JJ Barajas, VV Kouznetsov, E Stashenko, A Bahsas…
Index: Palma, Alirio; Barajas, Jacqueline Jaimes; Kouznetsov, Vladimir V.; Stashenko, Elena; Bahsas, Ali; Amaro-Luis, Juan Synlett, 2004 , # 15 p. 2721 - 2724
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Citation Number: 14
Abstract
In the synthesis of dibenz[b,e]azepines, anthranilic acid [9] and ortho-aminobenzylic alcohol [4] [10] derivatives as well as anthraquinone derivatives [11] are the most widely used precursors. However, to the best of our knowledge, the possibility to easily prepare this heterocyclic core using the broad scope of intramolecular alkene Friedel-Crafts alkylation in the series of N-benzyl-o-allylanilines has not been explored yet. ... In continuation of our research ...