Synthesis

Synthesis of a novel structural variant of imidazoquinazoline with three-point diversity

S Sharma, B Saha, D Sawant, B Kundu

Index: Sharma, Sunil; Saha, Biswajit; Sawant, Devesh; Kundu, Bijoy Synthesis, 2006 , # 11 p. 1841 - 1847

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Citation Number: 2

Abstract

Abstract An efficient strategy for the preparation of a novel structural variant of imidazoquinazolines with three-point diversity has been described. The compounds were obtained by treating benzil with o-nitrobenzaldehyde to give imidazoles, followed by reduction of the nitro group to give an aryl amine. Condensation-cyclization of the resulting intermediate with isothiocyanates in the presence of DBU for 45 minutes at room ...