Pd-catalyzed C3-selective allylation of indoles with allyl alcohols promoted by triethylborane

…, M Futamata, R Mukai, Y Tamaru

Index: Kimura, Masanari; Futamata, Makoto; Mukai, Ryutaro; Tamaru, Yoshinao Journal of the American Chemical Society, 2005 , vol. 127, # 13 p. 4592 - 4593

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Citation Number: 242

Abstract

Taking into consideration versatile reactivities of indoles as a nucleophile and π-allylpalladiums as an electrophile, it is rather surprising that only a few articles have appeared on the palladium-based allylation of indoles, which describe formation of either a mixture of N- and 3-allylindoles together with N,3-diallylindole, albeit in poor yields, 6 or N-allylindoles selectively in modest yield. 7 Nickel chemistry, on the other hand, seems to be more promising in ...

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