Tetrahedron

Copper (I)-catalyzed S-arylation of thiols with activated aryl chlorides on water

MT Herrero, R SanMartin, E Domínguez

Index: Herrero, Maria Teresa; SanMartin, Raul; Dominguez, Esther Tetrahedron, 2009 , vol. 65, # 7 p. 1500 - 1503

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Citation Number: 52

Abstract

Copper chloride-catalyzed S-arylation of arenethiols is effected with activated aryl chlorides in neat water by using ethylenediamine as the pair ligand/base. This convenient, environmentally more friendly procedure for the coupling of aryl chlorides allows the arylation between sterically demanding coupling partners.