Research on Chemical Intermediates

Substituted quinolinones. 18. 3-Acetyl-4-methylthioquinolin-2 (1H)-one as useful synthon intermediate for synthesis of some new quinolinones

MM Hassan, ES Othman, M Abass

Index: Hassan, Mohamed M.; Othman, Elham S.; Abass, Mohamed Research on Chemical Intermediates, 2013 , vol. 39, # 3 p. 1209 - 1225

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Citation Number: 6

Abstract

Abstract 3-Acetyl-4-methylthioquinolin-2 (1 H)-one (3) has been prepared and its reactivity towards treatment with different reagents, dilute sulfuric acid, aqueous sodium hydroxide, and hydrogen peroxide, is described. The reactions of compound 3 with benzylamine, benzaldehyde, DMF-DMA, Vilsmeier-Haack reagent, 2-chloro-3-formyl-pyridopyrimidone and malononitrile have been carried out under convenient conditions. Compound 3 ...