Assessment and use of two silicon carbide multi-well plates for library synthesis and proteolytic digests using microwave heating

…, CM Kormos, KB Avery, NE Leadbeater

Index: Stencel, Lauren M.; Kormos, Chad M.; Avery, Keri B.; Leadbeater, Nicholas E. Organic and Biomolecular Chemistry, 2009 , vol. 7, # 11 p. 2452 - 2457

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Citation Number: 9

Abstract

The use of two silicon carbide plates is reported for the preparation of three libraries of organic molecules using microwave heating. In addition, a preliminary study has been carried out, showing that one of the plates can also be used in a proteomics setting. Both the 24-position and 48-position plates heated evenly when irradiated with microwave energy. The 48-position plate was used to prepare a library of N-aryl functionalized β-amino esters ...