Synlett

Copper (I)-Catalyzed CC and CO Coupling Reactions Using Hydrazone Ligands

T Mino, F Yagishita, M Shibuya, K Kajiwara, H Shindo…

Index: Mino, Takashi; Yagishita, Fumitoshi; Shibuya, Masanori; Kajiwara, Kenji; Shindo, Hiroaki; Sakamoto, Masami; Fujita, Tsutomu Synlett, 2009 , # 15 p. 2457 - 2460

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Citation Number: 5

Abstract

Abstract Copper-catalyzed CC coupling reaction of aryl iodides with diethylmalonate in toluene at 90 C gave arylated malonates using 5 mol% of CuI with hydrazone 1a as a ligand in good yields under an aerobic atmosphere. We also found CuI/hydrazone 1b in toluene to be an efficient catalytic system for CO coupling reactions of aryl bromides with phenols to give aryl ethers in good yields at 110 C under an aerobic atmosphere.

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