Palladium??Catalyzed Decarboxylative Acylation of O??Phenyl Carbamates with α??Oxocarboxylic Acids at Room Temperature

S Sharma, A Kim, E Park, J Park, M Kim…

Index: Sharma, Satyasheel; Kim, Aejin; Park, Eonjeong; Park, Jihye; Kim, Minyoung; Kwak, Jong Hwan; Lee, Sang Hwi; Jung, Young Hoon; Kim, In Su Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 667 - 672

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Citation Number: 37

Abstract

Abstract A palladium-catalyzed oxidative acylation of O-phenyl carbamates with α- oxocarboxylic acids via selective aromatic C [BOND] H bond activation is described. This protocol represents the first ortho-acylation of phenol derivatives, and a catalytic amount of triflic acid additive is crucial for this transformation.