Synthesis, antimicrobial activity, and QSAR studies of furan-3-carboxamides

N Zanatta, SH Alves, HS Coelho, DM Borchhardt…

Index: Zanatta, Nilo; Alves, Sydney H.; Coelho, Helena S.; Borchhardt, Deise M.; Machado, Pablo; Flores, Kelen M.; da Silva, Fabio M.; Spader, Tatiana B.; Santurio, Janio M.; Bonacorso, Helio G.; Martins, Marcos A.P. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 5 p. 1947 - 1958

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Citation Number: 48

Abstract

The synthesis and characterization of a new series of furan-3-carboxamides, from the aromatization of 4-trichloroacetyl-2, 3-dihydrofuran to 3-trichloroacetyl furan followed by nucleophilic displacement of the trichloromethyl group or the corresponding carboxylic ...

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