Preparation of α-ketophosphonates by a [3, 3]-sigmatropoic shift of enolphosphonates

K Afarinkia, AJ Twist, H Yu

Index: Afarinkia, Kamyar; Twist, Andrew J.; Yu, Hiu-Wan Journal of Organometallic Chemistry, 2005 , vol. 690, # 10 p. 2688 - 2691

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Citation Number: 10

Abstract

One of the reactions of α-ketophosphonates which has as yet remained unexplored is their C-alkylation at the adjacent position to the C O. Indeed, there are very few examples in the literature pertaining to derivatization at the β-carbon of α-ketophosphonates. Two examples of halogenation of α-ketophosphonates are reported using either elemental bromine or chlorine [11], or sulfuryl chloride ( Scheme 1) [12]. No base is required for either reaction and it is not certain if the ...