Tetrahedron letters

Synthesis of substituted 4-(3-alkyl-1, 2, 4-oxadiazol-5-ylmethyl)-3, 4-dihydro-2H-1, 4-benzoxazines and 4-(1H-benzimidazol-2-ylmethyl)-3, 4-dihydro-2H-1, 4- …

P Mizar, B Myrboh

Index: Mizar, Pushpak; Myrboh, Bekington Tetrahedron Letters, 2006 , vol. 47, # 44 p. 7823 - 7826

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Citation Number: 15

Abstract

Substituted 2H-1, 4-benzoxazines were synthesized from substituted 2-amino phenols and 1, 2-dibromoethane using K2CO3 in good to excellent yields. The cyclized products were further reacted with alkyl bromides to obtain the desired N-substituted 3, 4-dihydro-2H-1, 4- benzoxazines.

Facile reduction of tertiary lactams to cyclic amines with 9-borabicyclo [3.3. 1] nonane (9-BBN)

[Collins, Christopher J.; Lanz, Marc; Singaram, Bakthan Tetrahedron Letters, 1999 , vol. 40, # 19 p. 3673 - 3676]

Palladium-catalyzed intramolecular CO bond formation

[Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L. Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908]

Dihydrobenzoxazines and tetrahydroquinoxalines by a tandem reduction??reductive amination reaction

[Bunce, Richard A.; Herron, Derrick M.; Hale, Lu Y. Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 6 p. 1031 - 1039]