The formation of the main skelton of bicyclomycin by the cyclization of 6-hydroxy-3-(3-hydroxypropyl)-2, 5-piperazinedione derivatives.

Y Sato, C Shin, S Sumiya, Y Nakajima…

Index: Sato; Shin; Sumiya; et al. Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 5 p. 1265 - 1270

Full Text: HTML

Citation Number: 5

Abstract

This paper describes the synthesis of 3-(3-t-butoxypropyl)-6-hydroxy-2, 5-piperazinedione derivatives by the hydroxylation of the corresponding 2, 5-piperazinedione with N- bromosuccinimide (NBS) in the presence of water and the subsequent cyclization to 2-oxa- 7, 9-diazabicyclo [4.2. 2] decane-8, 10-dione derivatives (11). The reversible interconversion between the spiro [oxolane-2, 2′-piperazine]-3′, 6′-dione prepared previously and the ...

Related Articles:

Facile syntheses of 3-spiro-and 3, 6-bridged 2, 5-piperazinediones

[Shin, Chung-gi; Sato, Yoshiaki; Yoshimura, Juji Tetrahedron Letters, 1981 , vol. 22, # 25 p. 2401 - 2404]

The synthesis and reaction of spiro (oxolane-2, 2'-piperazine)-3', 6'-diones with N-bromosuccinimide in the presence or absence of water.

[Shin; Sato; Honda; Yoshimura Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 9 p. 2652 - 2656]

Facile syntheses of 3-spiro-and 3, 6-bridged 2, 5-piperazinediones

[Shin, Chung-gi; Sato, Yoshiaki; Yoshimura, Juji Tetrahedron Letters, 1981 , vol. 22, # 25 p. 2401 - 2404]

Facile syntheses of 3-spiro-and 3, 6-bridged 2, 5-piperazinediones

[Shin, Chung-gi; Sato, Yoshiaki; Yoshimura, Juji Tetrahedron Letters, 1981 , vol. 22, # 25 p. 2401 - 2404]

Facile syntheses of 3-spiro-and 3, 6-bridged 2, 5-piperazinediones

[Shin, Chung-gi; Sato, Yoshiaki; Yoshimura, Juji Tetrahedron Letters, 1981 , vol. 22, # 25 p. 2401 - 2404]

More Articles...