Journal of Heterocyclic Chemistry

Synthesis of 3, 9b??dihydro??5H??pyrrolo [2, 1??a] isoindoles and 3, 5, 6, 10b??tetrahydropyrrolo [2, 1??a] isoquinolines with 1, 3??dipolar cycloaddition reactions

WK Anderson, FR Kinder

Index: Anderson, Wayne K.; Kinder, Frederick R. Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 4 p. 975 - 979

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Citation Number: 12

Abstract

Abstract The title classes of compounds have been prepared using a sequence of two ring- forming reactions. Initial 1, 3-dipolar cycloaddition with an azomethine ylide gave N-acylated 3-pyrrolines which were further elaborated to the target compounds by a tandem deprotection/cyclization reaction.