The Synthesis of Homodesthiobiotin and Related Compounds

H McKennis Jr, V Vigneaud

Index: McKennis; du Vigneaud Journal of the American Chemical Society, 1946 , vol. 68, p. 832,835

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Citation Number: 10

Abstract

4.25; neut. equiv., 164.7. Found: C, 65.33; H, 6.24; N, 4.17; neut. equiv., 162.0. We wish to thank Mr. A. Lanzilotti for tech- nical assistance in this investigation and Miss Edith Sozio for assistance in preparation of the manuscript. Summary 1. A general synthesis of l-arylcyclohexane- carboxylic acids has been described. 2. Certain esters of this general type show pronounced antispasmodic and some analgesic activity. NEWARK, NJ RECEIVED FEBRUARY 8, 1946

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