Tetrahedron letters

Improved preparation of angelate esters

B Hartmann, AM Kanazawa, JP Deprés, AE Greene

Index: Hartmann, Benoit; Kanazawa, Alice M.; Depres, Jean-Pierre; Greene, Andrew E. Tetrahedron Letters, 1991 , vol. 32, # 38 p. 5077 - 5080

Full Text: HTML

Citation Number: 44

Abstract

Abstract A new procedure has been developed for the efficient preparation of angelate esters from alcohols. The alcohol is treated in dry toluene at 70–80 C for 19–36 h with a mixed anhydride prepared from angelic acid and 2, 4, 6-trichlorobenzoyl chloride. In the absence of base, no tiglate ester is produced.