Journal of Heterocyclic Chemistry

The regiospecific synthesis of N??substituted pyrazoles. I. 1??and 2??substituted indeno [1, 2??c] pyrazol??4 (1H)??ones

TL Lemke, KN Sawhney

Index: Lemke, Thomas L.; Sawhney, Kailash N. Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1335 - 1340

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Citation Number: 9

Abstract

Abstract The reaction of the enaminoketones (2 or 5) of 2-acyl-1, 3-indandiones with unsymmetrical hydrazines results in the regiospecific synthesis of 1, 3-or 2, 3-disubstituted indeno [1, 2-c] pyrazol-4 (1H)-ones (4 or 7). The synthesis of the enaminoketones (2 or 5) is accomplished by way of amine addition to the 2-acyl-1, 3-indandiones 8a-c or by reduction of the indenoisoxazole 9. The structural assignment of the isomeric indenopyrazoles 4 ...