European Journal of Organic Chemistry

Synthesis of 6H??Isoindolo [2, 1??a] indol??6??ones Through Wittig Reaction and Tandem Reductive Cyclization–Lactamization

HK Kadam, SG Tilve

Index: Kadam, Hari K.; Tilve, Santosh G. European Journal of Organic Chemistry, 2013 , # 20 p. 4280 - 4284

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Citation Number: 5

Abstract

Abstract A convenient and efficient two-step route to 6H-Isoindolo [2, 1-a] indol-6-ones has been developed starting from o-nitrobenzaldehydes. The methodology involves Wittig reaction followed by tandem reductive cyclization–lactamization. A series of isoindoloindolones incorporating different substituents on the indole nucleus has been prepared.