Synthesis of novel 2-alkyl-4-substituted-amino-pyrazolo [3, 4-d] pyrimidines as new leads for anti-bacterial and anti-cancer activity

M Devarakonda, R Doonaboina, S Vanga…

Index: Devarakonda, Murty; Doonaboina, Raghava; Vanga, Sreedher; Vemu, Jahnavi; Boni, Sathoshini; Mailavaram, Raghu Prasad Medicinal Chemistry Research, 2013 , vol. 22, # 3 p. 1090 - 1101

Full Text: HTML

Citation Number: 7

Abstract

Abstract Treatment of 6-alkyl-1-phenyl-4-chloro-(1 H)-pyrazolo [3, 4-d] pyrimidines, with different amines afforded a series of compounds whose identity and purity were confirmed by spectral and analytical means. The compounds were tested for antibacterial activity against four organisms viz. Staphylococcus aureus (Gram positive), S. epidermidis (Gram positive), Bacillus subtilis (Gram positive), Escherichia coli (Gram negative) using ...

Related Articles:

Base-catalyzed one-pot tandem reaction: an effective strategy for the synthesis of pyrazolo [3, 4-d] pyrimidinone derivatives

[Reddy, K Hemender; Reddy, A Panduranga; Veeranagaiah, V Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 3 p. 163 - 166]

Synthesis of some Pyridothienopyrazolopyrimidopyrimidine and Mercaptomethylpyrazolopyrimidine derivatives

[Kamal El-Dean; Elkhawaga; Radwan, Sh. M.; Ahmed Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 8 p. 2034 - 2048]

More Articles...