Synthesis and antifungal activity of 1H-indole-4, 7-diones

CK Ryu, JY Lee, RE Park, MY Ma, JH Nho

Index: Ryu, Chung-Kyu; Lee, Jung Yoon; Park, Rae-Eun; Ma, Mi-Young; Nho, Ji-Hee Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 1 p. 127 - 131

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Citation Number: 42

Abstract

1H-Indole-4, 7-diones were synthesized and tested for in vitro antifungal activity against fungi. The synthesized 1H-indole-4, 7-diones generally showed good antifungal activity against Candida krusei, Cryptococcus neoformans, and Aspergillus niger. The results suggest that 1H-indole-4, 7-diones would be potent antifungal agents.