The Journal of organic chemistry

Nickel-catalyzed preparations of functionalized organozincs

S Vettel, A Vaupel, P Knochel

Index: Vettel, Stephan; Vaupel, Andrea; Knochel, Paul Journal of Organic Chemistry, 1996 , vol. 61, # 21 p. 7473 - 7481

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Citation Number: 74

Abstract

The reaction of primary alkyl bromides or chlorides with diethylzinc in the presence of Ni (acac) 2 (5 mol%) furnishes the corresponding alkylzinc halides (X= Br, Cl) via a halogen- zinc exchange reaction. The treatment of terminal alkenes with diethylzinc (neat, 25-60° C) in the presence of Ni (acac) 2 as a catalyst (1-5 mol%) and 1, 5-cyclooctadiene (COD) affords the corresponding dialkylzincs via a hydrozincation reaction. Whereas the ...

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