A general gold-catalyzed direct oxidative coupling of non-activated arenes

A Kar, N Mangu, HM Kaiser, M Beller…

Index: Kar, Anirban; Mangu, Naveenkumar; Kaiser, Hanns Martin; Beller, Matthias; Tse, Man Kin Chemical Communications, 2008 , # 3 p. 386 - 388

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Citation Number: 69

Abstract

Biaryls constitute an important structural component in natural products, pharmaceuticals, agrochemicals and materials. 1 In recent decades there have been rapid advances in C(sp 2 )–C(sp 2 ) bond formation reactions to construct biaryls. Traditionally, the arene being coupled needs to be 'pre-activated', such as by halogenation, prior to metal-mediated coupling reactions. 2 Alternatively, halogenated arenes are converted to organometallic reagents and homo- or ...