Carbamoyl radicals from carbamoylxanthates: a facile entry into isoindolin-1-ones

G López-Valdez, S Olguín-Uribe, LD Miranda

Index: Lopez-Valdez, German; Olguin-Uribe, Simon; Miranda, Luis D. Tetrahedron Letters, 2007 , vol. 48, # 47 p. 8285 - 8289

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Citation Number: 18

Abstract

It has been found that carbamoylxanthates derived from secondary t-butyl amines are stable compounds which function as efficient sources of carbamoyl radicals. The carbamoylxanthates derived from t-butylbenzylamines can be efficiently transformed into 2-t- butylisoindolin-1-ones via an oxidative radical cyclization process. The carbamoylxanthates derived from Nt-butylamino olefins underwent the expected cyclization/xanthate-transfer ...