Journal of medicinal chemistry

Synthesis and pharmacological activity of fluorinated tryptamine derivatives

A Kalir, S Szara

Index: Kalir,A.; Szara,S. J. Med. Chem., 1963 , vol. 6, p. 716 - 719

Full Text: HTML

Citation Number: 32

Abstract

Condensation of IIb with oxalyl chloride and treatment with diethylamine followed by reduction gave 6-fluoro-S, N-diethyltryptamine. l 2 Pharmacological Findings.-Compounds Ya, b were tested on mice using reserpine-induced ptosis reversal and activity cage tests. I3 In these tests,(see Fig. 1 and 2) Va acted like the parent compound, a-methyltryptamine, but there was a marked decrease in activity especially in the locomotor test with the 6-fluor0 ...

Related Articles:

Polyvinylpolypyrrolidone-bound boron trifluoride: A highly efficient catalyst for acylation of alcohols, phenols and trimethylsilyl ethers by acetic anhydride

[Mokhtary, Masoud; Qandalee, Mohammad; Najafizadeh, Faranak Comptes Rendus Chimie, 2012 , vol. 15, # 5 p. 389 - 393]

A Lewis acid-promoted Pinner reaction

[Pfaff, Dominik; Nemecek, Gregor; Podlech, Joachim Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1572 - 1577]

Solvent-free transesterification in a ball-mill over alumina surface

[Chatterjee, Tanmay; Saha, Debasree; Ranu, Brindaban C. Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4142 - 4144]

… -type zinc aluminate (ZnAl 2 O 4) nanoparticles prepared by the co-precipitation method: a novel, green and recyclable heterogeneous catalyst for the acetylation of …

[Farhadi, Saeid; Panahandehjoo, Somayeh Applied Catalysis A: General, 2010 , vol. 382, # 2 p. 293 - 302]

Electroreductive Acylation of Benzyl Chlorides with Acid Anhydrides. Stereoselective Formation of (E)-Enol Esters from Benzyl Alkyl Ketones.

[Nishiguchi, Ikuzo; Oki, Tsuneo; Hirashima, Tsuneaki; Shiokawa, Jiro Chemistry Letters, 1991 , p. 2005 - 2008]

More Articles...