Regioselectivity of the reactions of 4, 5??diphenylimidazole??2??thione with 1??chloro??2, 3??epoxy??propane and 1??bromo??propene, efficient precursors for imidazo [2, 1??b] …

M Aouad, NT Rezki, ESH El Ahsry

Index: Aouad, Mohamed R.; Rezki, Nadjet; El Ahsry, El Sayed H. Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1321 - 1327

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Citation Number: 6

Abstract

The imidazole core is a common moiety in a large number of natural products and pharmacologically active compounds [1]. Moreover, valuable biological applications such as antifungal [2], anti-thyroid [3] and antiasthmatic [4] activities have been associated with 2- thiosubstituted imidazoles. Its annulations with a thiazine or thiazole ring provide imidazo- thiazines and thiazoles with a wide spectrum of biological and pharmacological properties ...

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