Monatshefte für Chemie/Chemical Monthly

Anomalous dehydration of 2-phenylindole-3-carboxamide to 2-phenylindole-3-carbonitrile by lithium aluminum hydride

T Abraham, AJ Sicree

Index: Abraham, Tonson; Sicree, Albert J. Monatshefte fuer Chemie, 1982 , vol. 113, p. 1063 - 1066

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Abstract

Zusammenfassung Es wird gezeigt, daß für die anomale Dehydratisierung von 2- Phenylindol-3-carbonsäureamid (1) zum entsprechenden Nitril 3 durch Lithiumaluminiumhydrid sterische Faktoren verantwortlich sind. Dieser sterische Effekt zeigt sich auch bei Reaktionen von 2-Phenylindol (4) und seiner Derivate.

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