Palladium-catalyzed stille couplings of aryl-, vinyl-, and alkyltrichlorostannanes in aqueous solution

R Rai, KB Aubrecht, DB Collum

Index: Rai, Roopa; Aubrecht, Katherine B.; Collum, David B. Tetrahedron Letters, 1995 , vol. 36, # 18 p. 3111 - 3114

Full Text: HTML

Citation Number: 98

Abstract

Stille coupling of water-soluble aryl and vinyl halides with alkyl-, aryl-, and vinyltrichlorostannane derivatives (RSnCl3) are effected in aqueous solution using a catalyst generated in situ from PdCl2 and KOH both with and without added PhP (m-C6H4SO3Na) 2. The yields are generally good to excellent, although some limitations of the protocol are described.