The Journal of Organic Chemistry

Cyclization of 2-(4'-Carbomethoxy-2'-oxobutyl)-2-carbomethoxycyclohexanone1a

WL Meyer, BS Bielaski

Index: Meyer,W.L.; Bielaski,B.S. Journal of Organic Chemistry, 1963 , vol. 28, p. 2896 - 2897

Full Text: HTML

Citation Number: 2

Abstract

Systems like 2-(4'-carbomethoxy-2'-oxobutyl)-2-car-bomethoxycyclohexanone (I) can in principle undergo intramolecular aldol cyclization involving either the C-3'(a to the ketone, path A) or the C-4'(a to the ester, path B) methylene group. Since enolages are normally more readily generated from ketones than from esters one might well expect the former course, leading to the 2-hydrindenone derivative 11, to be favored in a ratecontrolled ...

Related Articles:

(±)-4-Oxo-9-deoxy-9-azaprostaglandin I2 derivatives. Very stable prostacyclin analogs

[Guzman; Martinez; Velarde; Maddox; Muchowski Canadian Journal of Chemistry, 1987 , vol. 65, # 9 p. 2164 - 2174]

(±)-4-Oxo-9-deoxy-9-azaprostaglandin I2 derivatives. Very stable prostacyclin analogs

[Guzman; Martinez; Velarde; Maddox; Muchowski Canadian Journal of Chemistry, 1987 , vol. 65, # 9 p. 2164 - 2174]

(±)-4-Oxo-9-deoxy-9-azaprostaglandin I2 derivatives. Very stable prostacyclin analogs

[Guzman; Martinez; Velarde; Maddox; Muchowski Canadian Journal of Chemistry, 1987 , vol. 65, # 9 p. 2164 - 2174]

More Articles...