A practical synthesis of polyhalomethyllithium-carbonyl adducts.

H Taguchi, H Yamamoto, H Nozaki

Index: Taguchi,H. et al. Bulletin of the Chemical Society of Japan, 1977 , vol. 50, # 6 p. 1588 - 1591

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Citation Number: 38

Abstract

The title adducts are produced upon treatment of a mixture of polyhalomethane and a carbonyl compound with a hindered lithium amide. The kinetically controlled, selective lithiation of the halide enables us to avoid a troublesome procedure involving preformed lithium carbenoid. The halide components examined are dichloromethane, dibromomethane, diiodomethane, chloroform, and bromoform, while the carbonyl ones ...