Diuretics: aminobenzenedisulfonamides

FC NOVELLO, SC BELL, ELA ABRAMS…

Index: Novello,F.C. et al. Journal of Organic Chemistry, 1960 , vol. 25, p. 965 - 970

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Citation Number: 26

Abstract

The diuretic activity of representative benzenedisulfonamides has been reported previously. 112, 3 Compounds of greatest interest lie in the meta series, derivatives of benzene-l, 3disulfonamide. The activity is markedly influenced by further substitution in the benzene ring; halogen, amino, and acylamino groups were found to be particularly desirable. The preparation and some of the structure-activity relations of a series of ...