Solvent-Free Synthesis of Tartramides Under Microwave Activation

F Massicot, R Plantier-Royon, C Portella, D Saleur…

Index: Massicot; Plantier-Royon; Portella; Saleur; Sudha Synthesis, 2001 , # 16 p. 2441 - 2444

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Citation Number: 24

Abstract

The preparation of amides from a carboxylic acid (aliphatic or aromatic) and an amine (primary or secondary) by a microwave-mediated process was previously studied and the conditions used gave good yields with primary amines and lower yields for hindered amines. [9] The use of imidazole to promote reaction of amines with sterically hindered carboxylic acids gave interesting results under mild irradiation conditions. [10] An efficient microwave energy absorption was ...