The First Example of Rhodium (I)-Catalyzed Regio-and Stereoselective Chloroesterification of Alkynes with Chloroformate Esters

R Hua, S Shimada, M Tanaka

Index: Hua; Shimada; Tanaka Journal of the American Chemical Society, 1998 , vol. 120, # 47 p. 12365 - 12366

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Citation Number: 58

Abstract

Hydroesterification of alkynes with carbon monoxide and alcohols1 or with formate esters2 is a process of great practical importance. However, the corresponding chloroesterification reaction, which provides a one-step synthesis of β-chloro-R, β-unsaturated esters with much synthetic potential, 3 has never been reported. In recent years we have been interested in transition metal complex-catalyzed addition reactions of EE′ bonds (E, E′) heteroatom ...