Development of Protein??Labeling Probes with a Redesigned Fluorogenic Switch Based on Intramolecular Association for No??Wash Live??Cell Imaging

Y Hori, K Nakaki, M Sato, S Mizukami…

Index: Hori, Yuichiro; Nakaki, Kyohei; Sato, Motoki; Mizukami, Shin; Kikuchi, Kazuya Angewandte Chemie - International Edition, 2012 , vol. 51, # 23 p. 5611 - 5614

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Citation Number: 25

Abstract

Fluorescence labeling of proteins is a powerful technique for studying precise protein localization and movement in living cells. Currently, fluorescent proteins (FPs) are the primary tools in this field owing to their technical feasibility and convenience.[1, 2] Although various FPs have been reported,[2] their properties such as protein size and brightness are not completely satisfactory for some biological applications.[1–3] As an alternative to FPs, ...