Synthesis and antibacterial activity of some novel bis-1, 2, 4-triazolo [3, 4-b]-1, 3, 4-thiadiazoles and bis-4-thiazolidinone derivatives from terephthalic dihydrazide

VS Palekar, AJ Damle, SR Shukla

Index: Palekar, Vikrant S.; Damle, Amey J.; Shukla European Journal of Medicinal Chemistry, 2009 , vol. 44, # 12 p. 5112 - 5116

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Citation Number: 93

Abstract

A novel series of 1, 4-bis (6-(substituted phenyl)-[1, 2, 4]-triazolo [3, 4-b]-1, 3, 4-thiadiazoles (5a–b) and 4-bis (substituted phenyl)-4-thiazolidinone derivatives (7a–c) have been synthesized from terephthalic dihydrazide (1) through multistep reaction sequence. 1, 4-Bis (5-aryl-1, 3, 4-oxadiazole-2yl) benzene derivatives (2a–f) and bis-substituted terephthalohydrazide (6a–e) were also synthesized from terephthalic dihydrazide by ...

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