3-haloquinolines by friedlander reaction of α-haloketones
SV Ryabukhin, VS Naumchik, AS Plaskon…
Index: Ryabukhin, Sergey V.; Naumchik, Vasiliy S.; Plaskon, Andrey S.; Grygorenko, Oleksandr O.; Tolmachev, Andrey A. Journal of Organic Chemistry, 2011 , vol. 76, # 14 p. 5774 - 5781
Full Text: HTML
Citation Number: 30
Abstract
A general approach to 3-fluoro-, 3-chloro-, and 3-bromoquinolines which relies on organosilane-promoted Friedländer reaction of α-haloketones is described. The scope of the methylene component as well as influence of the organosilane component on the outcome of the reaction is studied. The method can be used under parallel synthesis conditions.
Related Articles:
[Angelis, Francesco De; Inesi, Achille; Feroci, Marta; Nicoletti, Rosario Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 445 - 447]
[Angelis, Francesco De; Inesi, Achille; Feroci, Marta; Nicoletti, Rosario Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 445 - 447]
[Angelis, Francesco De; Inesi, Achille; Feroci, Marta; Nicoletti, Rosario Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 445 - 447]
[Joshi, Krishna C.; Jain, Renuka; Arora, Seema Journal of the Indian Chemical Society, 1993 , vol. 70, # 6 p. 567 - 568]
[Botta, M.; Angelis, F. De; Gambacorta, A. Tetrahedron, 1982 , vol. 38, # 15 p. 2315 - 2318]