Fe (III)-catalyzed cross-coupling between functionalized arylmagnesium compounds and alkenyl halides

W Dohle, F Kopp, G Cahiez, P Knochel

Index: Dohle; Kopp; Cahiez; Knochel Synlett, 2001 , # 12 p. 1901 - 1904

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Citation Number: 24

Abstract

Abstract: Functionalized arylmagnesium reagents bearing an ester, cyano, nonaflate or trialkylsilyloxy group undergo fast cross-coupling reactions with alkenyl iodides or bromides in the presence of catalytic amounts of Fe (acac) 3 (5 mol%) at–20 C within 1 hour resulting in the formation of the desired cross-coupling products in satisfactory yields. Excellent yields can be achieved by performing the cross-coupling reaction on solid phase by generating ...