Tetrahedron Letters

Reductive amination of carbonyl compounds using NaBH 4 in a Brønsted acidic ionic liquid

PS Reddy, S Kanjilal, S Sunitha, RBN Prasad

Index: Reddy, P. Srinivasa; Kanjilal, Sanjit; Sunitha; Prasad, Rachapudi B.N. Tetrahedron Letters, 2007 , vol. 48, # 50 p. 8807 - 8810

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Citation Number: 53

Abstract

Reductive amination of carbonyl compounds using sodium borohydride is conducted in the Brønsted acidic ionic liquid, 1-methyl imidazolium tetrafluoroborate ([HMIm][BF4]). The ionic liquid plays the dual role of solvent as well as catalyst for efficient conversion of aldehydes and ketones to amines in excellent yields without the formation of side products.

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