A Synthetic Route to α??Substituted Butenolides: Enantioselective Synthesis of (+)??Ancepsenolide

C Ghobril, J Kister, R Baati

Index: Ghobril, Cynthia; Kister, Jeremy; Baati, Rachid European Journal of Organic Chemistry, 2011 , # 19 p. 3416 - 3419

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Citation Number: 8

Abstract

Abstract A variety of α-substituted butenolides was efficiently synthesized starting from commercially available tetronic acid and carboxylic acids in four steps. The effectiveness of this approach is illustrated in the short synthesis of one of the first butenolide acetogenins:(+)- ancepsenolide.